There are various drugs for the treatment of different diseases.
The Liver diseases have been listed down in alphabetical order. Click
on the alphabet to read more about the diseases.
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Hepatic
hemangioma
There is no specific medication indicated
for treatment
Hemochromatosis
| Treatment |
Indication |
Dose |
| Deferoxamine |
This drug binds to and helps rid
the body of iron. However, it is almost never
necessary because of the ease and efficacy of
phlebotomy therapy (removal of blood). |
500-1000 mg by intramuscular
injection once daily.
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Hemophilia
| Treatment |
Indication |
Dose |
| Desmopressin |
This medication can be used in patients with mild hemophilia A to increase levels of factor 8, a component of blood that helps in blood clotting. |
0.3 micrograms per kg of body
weight by intravenous or subcutaeous administration
(maximum 20 micrograms) diluted in 50 mL of
normal saline infused over 20 to 30 minutes.Alternative
is 150-300 micrograms by intranasal spray
(1 spray in each nostril).
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| Tranexaminic acid |
This medication prevents
the breakdown of blood clots, and is used to stabilize
bleeding from nosebleeds, menstruation, and oral
cavity bleeding. |
25 mg per kg of body
weight by mouth or by intravenous administration
every six to eight hours. |
| Aminocaproic acid |
This medication prevents
the breakdown of blood clots, and is used to stabilize
bleeding from nosebleeds, menstruation, and oral
cavity bleeding. |
75 to 100 mg per kg
of body weight by mouth or by intravenous administration
every six hours (maximum single dose 3 to 4 g).
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| Factor 8 or 9 replacement
products |
These products are
synthetic analogs of the components of blood that
help in clotting and are deficient in hemophilia
A or B. |
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Hepatitis
A
There is no specific medication indicated for treatment.
Hepatitis
B
| Treatment |
Indication |
Dose |
| Interferon |
The main role of interferon
is treatment of young patients with well compensated
liver disease, who do not wish to be on long-term
treatment, and in whom drug resistance may limit
their treatment options in the future. |
5 million units once daily or
10 MU three times a week by subcutaneous administration
or intramuscular injection for 16 to 32 weeks
(if also infected with hepatitis E) or 12
to 24 weeks (if not infected with hepatitis
E).
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| Pegylated interferon |
The main role of interferon
is treatment of young patients with well compensated
liver disease, who do not wish to be on long-term
treatment, and in whom drug resistance may limit
their treatment options in the future. |
180 mcg by subcutaneous
administration once weekly for 48 weeks. |
| Lamivudine |
Its main role currently
is in patients who also have HIV, and for short-term
treatment in patients who are receiving cancer
chemotherapy. Also, this medication is cheaper
than the other options. |
100 mg by mouth once
daily. |
| Adevofir |
The most important
role of adefovir is in the treatment of patients
with lamivudine-resistant HBV. |
10 mg by mouth once
daily. |
| Entecavir |
Entecavir has a more important
role in primary treatment of HBV than in patients
with lamivudine-resistant HBV. Entecavir may also
have an important role in patients with decompensated
cirrhosis because of its potent antiviral activity
and low rate of drug resistance. However, it is
a new drug and its safety as well as rate of drug
resistance with long-term use is unknown. |
0.5 – 1 mg by
mouth once daily. |
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Contraindications
and side-effects of medications
| Medication |
Reasons not to take this medicine |
Side-effects |
| Adefovir |
If you have an allergy
to adefovir or any other part of this medicine.
If you are breast-feeding. |
Worsening kidney function.
Headache.
Nausea or vomiting. Small frequent meals,
frequent mouth care, sucking hard, sugar-free
candy, or chewing sugar-free gum may help.
Diarrhea.
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| Aminocaproic acid |
If you have an allergy
to aminocaproic acid or any other part of this
medicine. |
Headache.
Nausea or vomiting. Small frequent meals, frequent
mouth care, sucking hard, sugar-free candy, or
chewing sugar-free gum may help.
Belly pain.
Nasal congestion. |
| Deferoxamine |
If you have an allergy
to deferoxamine or any other part of this medicine.
If you have severe kidney disease. |
Bluish fingernails,
lips, or skin.
Blurred vision or other problems with vision.
Convulsions (seizures).
Difficulty in breathing or fast breathing
Fast heartbeat
Hearing problems Pain or swelling at place of
injectionRedness or flushing of skin, skin rash,
hives, or itching.
Diarrhea.
Nausea or vomiting. Small frequent meals, frequent
mouth care, sucking hard, sugar-free candy, or
chewing sugar-free gum may help.
Difficulty with urination.
Fever.
Leg cramps, stomach and muscle cramps.
Unusual bleeding or bruising.
Deferoxamine may cause the urine to turn orange-rose
in color. |
| Desmopressin |
Do not give this medicine
to a child younger than 6 years of age.
If you have an allergy to desmopressin acetate
or any other part of this medicine. |
Headache.
Belly pain.
Nausea or vomiting. Small frequent meals, frequent
mouth care, sucking hard, sugar-free candy, or
chewing sugar-free gum may help. |
| Entecavir |
If you have an allergy
to entecavir or any other part of this medicine.
If you are breast-feeding. |
Increased liver enzymes.
Blood or sugar in the urine.
Headache.
Nausea or vomiting. Small frequent meals, frequent
mouth care, sucking hard, sugar-free candy, or
chewing sugar-free gum may help.Diarrhea. |
| Interferon |
If you have an allergy
to interferon or any other part of this medicine.
If you are pregnant or breast-feeding. |
Anxiety, depression,
trouble sleeping, difficulty concentrating.
Black, tarry stools, blood in stools.
Confusion.
Cough or hoarseness.
Fever or chills.
Lower back or side pain.
Painful or difficult urination, blood in urine.
Pinpoint red spots on skin, redness at place of
injection, unusual bleeding or bruising.
Chest pain, irregular heartbeat.
Numbness or tingling of fingers, toes, or face.
Abdominal pain.
Aching muscles.
Decreased appetite.
Diarrhea.
Dizziness.
Headache.
Heartburn or indigestion.
Nausea or vomiting. Small frequent meals, frequent
mouth care, sucking hard, sugar-free candy, or
chewing sugar-free gum may help.
Pain in back or joints.
Sore throat.
General feeling of tiredness or weakness.
Interferon alfacon-1 may cause a temporary loss
of some hair. After treatment has ended, normal
hair growth should return. |
| Lamivudine |
If you have an allergy
to lamivudine or any other part of this medicine.
If you are pregnant or may be pregnant.
If you are breast-feeding. |
Headache.
Nausea or vomiting. Small frequent meals, frequent
mouth care, sucking hard, sugar-free candy, or
chewing sugar-free gum may help.
Diarrhea.
Irritated pancreas can rarely occur. |
| Tranexaminic acid |
If you have an allergy
to tranexaminic acid or any other part of this
medicine.
If you have defective color vision.
If you are actively bleeding in your brain. |
Nausea or vomiting.
Small frequent meals, frequent mouth care, sucking
hard, sugar-free candy, or chewing sugar-free
gum may help.
Diarrhea.
Blurred vision
Low blood pressure
Blood clot in legs
Kidney failure |
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Hepatitis
C
| Treatment |
Indication |
Dose |
| Interferon alpha or
pegylated interferon |
These medications
should preferably be administered within clinical
trials.
|
5 million units by subcutaneous
administration once daily for four weeks followed
by 5 million units by subcutaneous administration
three times a week for 20 weeks.
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| Ribavarin |
This medication should
preferably be administered within clinical trials,
usually in combination with interferon. |
500-600 mg by
mouth twice a day for 48 weeks in combination
with pegylated interferon 2a-alpha.
Alternative is 400 mg by mouth once daily for
1 year in combination with pegylated interferon
2b-alpha.
Alternative is 400-600 mg by mouth in the morning
then 600 mg by mouth in the evening for 48 weeks
in combination with interferon alpha 2b. |
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